Arizona Diamondbacks| Date | Transaction |
| 06/27/2012 | Stephen Drew Recalled From Minors Rehab |
| 06/27/2012 | Jonathan Albaladejo Sent to Minors |
| 06/27/2012 | Patrick Corbin Called Up from Minors |
| 06/24/2012 | David Hernandez Signed; two-year extension |
| 06/23/2012 | Jonathan Albaladejo Called Up from Minors |
| 06/16/2012 | Geoff Blum Sent to Minors for Rehabilitation |
| 06/08/2012 | Lyle Overbay Reinstated from Paternity Leave List |
| 06/07/2012 | Stephen Drew Sent to Minors for Rehabilitation |
| 06/07/2012 | A.J. Pollock Sent to Minors |
| 06/06/2012 | Lyle Overbay Placed on Paternity Leave List |
| 06/06/2012 | A.J. Pollock Called Up from Minors |
| 06/05/2012 | Takashi Saito Sent to Minors for Rehabilitation |
| 06/01/2012 | Jason Kubel Reinstated from Paternity Leave List |
| 06/01/2012 | A.J. Pollock Sent to Minors |
| 05/30/2012 | Jason Kubel Placed on Paternity Leave List |
| 05/30/2012 | A.J. Pollock Called Up from Minors |
| 05/27/2012 | Daniel Hudson Recalled From Minors Rehab |
| 05/26/2012 | Miguel Montero Signed; five-year extension |
| 05/26/2012 | Konrad Schmidt Sent to Minors |
| 05/23/2012 | Cody Ransom Acquired Off Waivers to Milwaukee Brewers |
| 05/22/2012 | Konrad Schmidt Called Up from Minors |
| 05/22/2012 | Patrick Corbin Sent to Minors |
| 05/21/2012 | Cody Ransom Designated for Assignment |
| 05/21/2012 | Daniel Hudson Sent to Minors for Rehabilitation |
| 05/21/2012 | Josh Bell Called Up from Minors |
| 05/18/2012 | Chris Young Recalled From Minors Rehab |
| 05/18/2012 | A.J. Pollock Sent to Minors |
| 05/16/2012 | David Winfree NTR - Called Up From Minors |
| 05/16/2012 | David Winfree Outrighted to Minors |
| 05/14/2012 | Chris Young Sent to Minors for Rehabilitation |
| 04/30/2012 | Geoff Blum Transferred to 60-Day DL; Strained left oblique |
| 04/30/2012 | Joe Martinez Sent to Minors |
| 04/30/2012 | Patrick Corbin Purchased From Minors |
| 04/27/2012 | Jonathan Albaladejo Sent to Minors |
| 04/24/2012 | Mike Zagurski Purchased From Minors |
| 04/24/2012 | Jonathan Albaladejo Designated for Assignment |
| 04/24/2012 | Joe Martinez Called Up from Minors |
| 04/24/2012 | Joe Paterson Sent to Minors |
| 04/21/2012 | Takashi Saito Recalled From Minors Rehab |
| 04/21/2012 | Jonathan Albaladejo Called Up from Minors |
| 04/21/2012 | Josh Bell Sent to Minors |
| 04/21/2012 | Josh Bell Traded from Baltimore Orioles; for LHP Mike Belfiore |
| 04/19/2012 | Takashi Saito Sent to Minors for Rehabilitation |
| 04/18/2012 | Cody Ransom Purchased From Minors |
| 04/18/2012 | Brent Clevlen Signed to a Minor League Contract |
| 04/18/2012 | Daniel Stange Released |
| 04/18/2012 | A.J. Pollock Purchased From Minors |
| 04/14/2012 | David Winfree Sent to Minors |
| 04/04/2012 | Mike Zagurski Outrighted to Minors |
| 03/28/2012 | Craig Tatum Acquired Off Waivers to New York Yankees |
| 03/23/2012 | Sam Demel Sent to Minors |
| 03/23/2012 | Barry Enright Sent to Minors |
| 03/23/2012 | Trevor Bauer Sent to Minors |
| 03/23/2012 | David Winfree Sent to Minors; voided by MLB per injury settlement |
| 03/23/2012 | David Winfree Voided Option |
| 03/17/2012 | Zach Kroenke Called Up from Minors |
| 03/17/2012 | Zach Kroenke Outrighted to Minors |
| 03/15/2012 | Jonathan Albaladejo Sent to Minors |
| 03/15/2012 | Joe Martinez Sent to Minors |
| 03/15/2012 | Cole Gillespie Sent to Minors |
| 03/15/2012 | Zach Kroenke Sent to Minors |
| 03/15/2012 | Konrad Schmidt Sent to Minors |
| 03/07/2012 | Randy Ruiz Signed to a Minor League Contract |
| 02/29/2012 | Kevin Mulvey Released |
| 02/08/2012 | Craig Breslow Signed; avoids arbitration |
| 01/31/2012 | Ryan Roberts Signed; avoids arbitration |
| 01/31/2012 | Miguel Montero Signed; avoids arbitration |
| 01/25/2012 | Daryle Ward Suspension Announced By League; 50 games for violating MLB drug program |
| 01/24/2012 | Brad Ziegler Signed; avoids arbitration |
| 01/23/2012 | Craig Tatum Acquired Off Waivers from Houston Astros |
| 01/18/2012 | Joe Saunders Signed as Free Agent; one-year contract |
| 01/04/2012 | Mike Jacobs Signed to a Minor League Contract |
| 12/29/2011 | Melvin Mora Retired |
| 12/20/2011 | Jason Kubel Signed as Free Agent; two-year contract |
| 12/16/2011 | Takashi Saito Signed as Free Agent; one-year contract |
| 12/14/2011 | Jonathan Albaladejo Signed as Free Agent; one-year contract |
| 12/12/2011 | Lyle Overbay Signed as Free Agent; one-year contract |
| 12/12/2011 | Joe Saunders Free Agent - No Contract Offer; non-tendered |
| 12/12/2011 | Micah Owings Free Agent - No Contract Offer; non-tendered |
| 12/11/2011 | Cody Ransom Signed to a Minor League Contract |
| 12/09/2011 | Jason Lane Signed to a Minor League Contract |
| 12/09/2011 | Craig Breslow Traded from Oakland Athletics; with RHP Trevor Cahill, five-player deal |
| 12/09/2011 | Trevor Cahill Traded from Oakland Athletics; with LHP Craig Breslow, five-player deal |
| 12/09/2011 | Jarrod Parker Traded to Oakland Athletics; for RHP Trevor Cahill, five-player deal |
| 12/09/2011 | Collin Cowgill Traded to Oakland Athletics; for RHP Trevor Cahill, five-player deal |
| 12/09/2011 | Ryan Cook Traded to Oakland Athletics; for RHP Trevor Cahill, five-player deal |
| 12/06/2011 | Joe Martinez Signed as Free Agent; one-year contract |
| 11/29/2011 | Jensen Lewis Signed to a Minor League Contract |
| 11/16/2011 | Aaron Hill Signed as Free Agent; two-year contract |
| 11/16/2011 | Rusty Ryal Signed to a Minor League Contract |
| 11/15/2011 | Ryan Budde Signed to a Minor League Contract |
| 11/14/2011 | Kam Mickolio Signed to Play in Japan; Hiroshima Toyo Carp |
| 11/10/2011 | Kam Mickolio Cleared Waivers and Became a Free Agent |
| 11/09/2011 | Willie Bloomquist Signed as Free Agent; two-year contract |
| 11/08/2011 | Chris Jakubauskas Signed to a Minor League Contract |
| 11/07/2011 | Kam Mickolio Released |
| 11/04/2011 | Henry Blanco Signed as Free Agent; one-year contract |
| 11/03/2011 | John McDonald Signed as Free Agent; two-year contract |