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| Career Leaders | MLB Leaders | AL Leaders | NL Leaders | Team Leaders |
| Rank | Player | Team | ERA | W | L | S | SvO | G | GS | CG | SO | IP | H | R | ER | HR | BB | K | QS | Ratio | BAVG |
| 1 | R.A. Dickey | NYM | 2.00 | 11 | 1 | 0 | 0 | 14 | 14 | 3 | 2 | 99 | 67 | 24 | 22 | 8 | 21 | 103 | 13 | 0.89 | .194 |
| 2 | Matt Cain | SF | 2.34 | 9 | 2 | 0 | 0 | 14 | 14 | 2 | 2 | 100 | 71 | 30 | 26 | 8 | 20 | 100 | 10 | 0.91 | .199 |
| Jered Weaver | LAA | 2.40 | 7 | 1 | 0 | 0 | 12 | 12 | 2 | 1 | 75 | 51 | 23 | 20 | 5 | 17 | 60 | 9 | 0.91 | .189 | |
| 4 | Jake Peavy | CWS | 2.74 | 6 | 3 | 0 | 0 | 14 | 14 | 3 | 1 | 98.2 | 70 | 32 | 30 | 8 | 23 | 83 | 12 | 0.94 | .198 |
| 5 | James McDonald | PIT | 2.19 | 6 | 3 | 0 | 0 | 14 | 14 | 1 | 0 | 90.1 | 62 | 24 | 22 | 4 | 24 | 83 | 10 | 0.95 | .195 |
| 6 | Brandon Beachy | ATL | 2.00 | 5 | 5 | 0 | 0 | 13 | 13 | 1 | 1 | 81 | 49 | 24 | 18 | 6 | 29 | 68 | 8 | 0.96 | .171 |
| Chris Sale | CWS | 2.24 | 8 | 2 | 0 | 1 | 14 | 13 | 1 | 0 | 88.1 | 62 | 23 | 22 | 4 | 23 | 89 | 9 | 0.96 | .194 | |
| 8 | Justin Verlander | DET | 2.57 | 7 | 4 | 0 | 0 | 15 | 15 | 3 | 1 | 108.2 | 81 | 37 | 31 | 6 | 27 | 106 | 12 | 0.99 | .204 |
| 9 | Colby Lewis | TEX | 3.00 | 6 | 5 | 0 | 0 | 14 | 14 | 2 | 0 | 96 | 84 | 39 | 32 | 15 | 12 | 84 | 10 | 1.00 | .231 |
| Brandon Morrow | TOR | 3.01 | 7 | 4 | 0 | 0 | 13 | 13 | 3 | 3 | 77.2 | 54 | 28 | 26 | 7 | 24 | 67 | 8 | 1.00 | .194 | |
| 11 | Clayton Kershaw | LAD | 2.73 | 5 | 3 | 0 | 0 | 15 | 15 | 1 | 1 | 102.1 | 78 | 34 | 31 | 10 | 25 | 95 | 10 | 1.01 | .214 |
| 12 | Ryan Dempster | CHC | 2.11 | 3 | 3 | 0 | 0 | 12 | 12 | 0 | 0 | 81 | 61 | 21 | 19 | 6 | 22 | 66 | 9 | 1.02 | .204 |
| 13 | Stephen Strasburg | WAS | 2.46 | 9 | 1 | 0 | 0 | 14 | 14 | 0 | 0 | 84 | 65 | 26 | 23 | 6 | 22 | 110 | 11 | 1.04 | .214 |
| 14 | Gio Gonzalez | WAS | 2.55 | 9 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 84.2 | 55 | 24 | 24 | 1 | 34 | 101 | 11 | 1.05 | .182 |
| Edwin Jackson | WAS | 3.02 | 3 | 4 | 0 | 0 | 13 | 13 | 1 | 0 | 86.1 | 66 | 31 | 29 | 8 | 25 | 63 | 9 | 1.05 | .213 | |
| 16 | Wade Miley | ARI | 2.30 | 8 | 3 | 0 | 0 | 14 | 11 | 0 | 0 | 82.1 | 70 | 24 | 21 | 3 | 17 | 57 | 8 | 1.06 | .225 |
| 17 | Madison Bumgarner | SF | 2.92 | 8 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 95.2 | 83 | 36 | 31 | 8 | 19 | 78 | 8 | 1.07 | .231 |
| 18 | Cole Hamels | PHI | 3.25 | 10 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 97 | 84 | 38 | 35 | 11 | 22 | 99 | 10 | 1.09 | .234 |
| 19 | Matt Garza | CHC | 4.07 | 3 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 77.1 | 64 | 38 | 35 | 11 | 22 | 72 | 9 | 1.11 | .223 |
| Kyle Lohse | STL | 2.85 | 6 | 2 | 0 | 0 | 15 | 15 | 0 | 0 | 94.2 | 90 | 33 | 30 | 8 | 15 | 54 | 10 | 1.11 | .250 | |
| 21 | Jason Hammel | BAL | 2.61 | 8 | 2 | 0 | 0 | 14 | 14 | 1 | 1 | 89.2 | 71 | 29 | 26 | 7 | 29 | 87 | 8 | 1.12 | .215 |
| Cliff Lee | PHI | 3.48 | 0 | 3 | 0 | 0 | 11 | 11 | 0 | 0 | 77.2 | 73 | 30 | 30 | 9 | 14 | 77 | 7 | 1.12 | .253 | |
| Johan Santana | NYM | 3.00 | 5 | 3 | 0 | 0 | 14 | 14 | 2 | 2 | 84 | 66 | 30 | 28 | 8 | 28 | 84 | 8 | 1.12 | .214 | |
| Jordan Zimmermann | WAS | 2.89 | 3 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 90.1 | 84 | 32 | 29 | 11 | 17 | 64 | 12 | 1.12 | .246 | |
| 25 | Mark Buehrle | MIA | 3.82 | 5 | 8 | 0 | 0 | 14 | 14 | 1 | 0 | 92 | 92 | 42 | 39 | 12 | 13 | 44 | 9 | 1.14 | .263 |
| Chris Capuano | LAD | 2.71 | 8 | 2 | 0 | 0 | 14 | 14 | 0 | 0 | 86.1 | 67 | 30 | 26 | 10 | 31 | 80 | 9 | 1.14 | .217 | |
| 27 | Josh Beckett | BOS | 4.14 | 4 | 7 | 0 | 0 | 12 | 12 | 0 | 0 | 78.1 | 73 | 36 | 36 | 9 | 17 | 56 | 8 | 1.15 | .247 |
| Johnny Cueto | CIN | 2.38 | 8 | 3 | 0 | 0 | 14 | 14 | 2 | 0 | 94.2 | 89 | 27 | 25 | 5 | 20 | 67 | 11 | 1.15 | .251 | |
| Roy Halladay | PHI | 3.98 | 4 | 5 | 0 | 0 | 11 | 11 | 0 | 0 | 72.1 | 69 | 32 | 32 | 6 | 14 | 56 | 8 | 1.15 | .252 | |
| Lance Lynn | STL | 2.80 | 10 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 86.2 | 71 | 28 | 27 | 5 | 29 | 90 | 9 | 1.15 | .223 | |
| Ryan Vogelsong | SF | 2.41 | 6 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 89.2 | 71 | 25 | 24 | 6 | 32 | 64 | 12 | 1.15 | .219 | |
| C.J. Wilson | LAA | 2.44 | 8 | 4 | 0 | 0 | 15 | 15 | 0 | 0 | 92.1 | 67 | 31 | 25 | 4 | 39 | 79 | 12 | 1.15 | .203 | |
| 33 | Shaun Marcum | MIL | 3.39 | 5 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 82.1 | 70 | 33 | 31 | 10 | 26 | 77 | 9 | 1.17 | .227 |
| 34 | Zack Greinke | MIL | 2.81 | 8 | 2 | 0 | 0 | 15 | 15 | 0 | 0 | 96 | 92 | 31 | 30 | 3 | 21 | 99 | 11 | 1.18 | .253 |
| 35 | Brandon McCarthy | OAK | 2.54 | 6 | 3 | 0 | 0 | 12 | 12 | 0 | 0 | 78 | 75 | 25 | 22 | 5 | 19 | 52 | 9 | 1.21 | .252 |
| Tommy Milone | OAK | 4.13 | 7 | 5 | 0 | 0 | 14 | 14 | 1 | 0 | 89.1 | 84 | 43 | 41 | 13 | 24 | 52 | 7 | 1.21 | .247 | |
| Anibal Sanchez | MIA | 3.94 | 3 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 89 | 80 | 43 | 39 | 8 | 28 | 83 | 10 | 1.21 | .242 | |
| 38 | Jason Vargas | SEA | 4.66 | 7 | 7 | 0 | 0 | 16 | 16 | 0 | 0 | 102.1 | 98 | 53 | 53 | 20 | 27 | 64 | 8 | 1.22 | .254 |
| 39 | CC Sabathia | NYY | 3.55 | 9 | 3 | 0 | 0 | 14 | 14 | 1 | 0 | 101.1 | 98 | 45 | 40 | 10 | 27 | 102 | 9 | 1.23 | .250 |
| 40 | A.J. Burnett | PIT | 3.24 | 8 | 2 | 0 | 0 | 12 | 12 | 0 | 0 | 75 | 66 | 28 | 27 | 6 | 27 | 62 | 9 | 1.24 | .235 |
| Dillon Gee | NYM | 4.27 | 5 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 90.2 | 87 | 47 | 43 | 12 | 25 | 83 | 10 | 1.24 | .250 | |
| 42 | Joe Blanton | PHI | 5.04 | 6 | 6 | 0 | 0 | 15 | 14 | 2 | 1 | 91 | 102 | 55 | 51 | 17 | 12 | 74 | 6 | 1.25 | .277 |
| Matt Harrison | TEX | 3.41 | 9 | 3 | 0 | 0 | 14 | 14 | 1 | 1 | 92.1 | 93 | 36 | 35 | 7 | 22 | 55 | 10 | 1.25 | .261 | |
| 44 | Trevor Cahill | ARI | 3.47 | 6 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 90.2 | 80 | 38 | 35 | 4 | 34 | 67 | 8 | 1.26 | .245 |
| Wandy Rodriguez | HOU | 3.29 | 6 | 5 | 0 | 0 | 15 | 15 | 0 | 0 | 95.2 | 99 | 44 | 35 | 12 | 22 | 61 | 10 | 1.26 | .265 | |
| 46 | Jonathon Niese | NYM | 3.75 | 5 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 81.2 | 75 | 37 | 34 | 13 | 29 | 79 | 9 | 1.27 | .241 |
| David Price | TB | 3.08 | 9 | 4 | 0 | 0 | 14 | 14 | 1 | 1 | 90.2 | 84 | 33 | 31 | 7 | 31 | 82 | 9 | 1.27 | .248 | |
| 48 | Hector Noesi | SEA | 5.69 | 2 | 8 | 0 | 0 | 14 | 14 | 0 | 0 | 80.2 | 73 | 52 | 51 | 15 | 30 | 50 | 6 | 1.28 | .246 |
| 49 | Bruce Chen | KC | 4.81 | 6 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 82.1 | 88 | 45 | 44 | 9 | 18 | 59 | 7 | 1.29 | .272 |
| Wei-Yin Chen | BAL | 3.36 | 7 | 2 | 0 | 0 | 13 | 13 | 0 | 0 | 80.1 | 79 | 34 | 30 | 8 | 25 | 57 | 7 | 1.29 | .256 | |
| Kevin Correia | PIT | 4.12 | 3 | 6 | 0 | 0 | 13 | 13 | 0 | 0 | 74.1 | 74 | 36 | 34 | 12 | 22 | 27 | 6 | 1.29 | .261 | |
| Felix Hernandez | SEA | 3.52 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 94.2 | 92 | 39 | 37 | 9 | 30 | 91 | 8 | 1.29 | .256 | |
| Ian Kennedy | ARI | 4.13 | 5 | 7 | 0 | 0 | 14 | 14 | 1 | 0 | 89.1 | 95 | 42 | 41 | 11 | 20 | 81 | 9 | 1.29 | .271 | |
| Hiroki Kuroda | NYY | 3.57 | 6 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 88.1 | 86 | 38 | 35 | 12 | 28 | 62 | 8 | 1.29 | .257 | |
| Clayton Richard | SD | 3.95 | 5 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 98 | 99 | 53 | 43 | 12 | 27 | 58 | 9 | 1.29 | .259 | |
| 56 | Bartolo Colon | OAK | 4.22 | 6 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 89.2 | 101 | 43 | 42 | 12 | 16 | 55 | 7 | 1.30 | .283 |
| Gavin Floyd | CWS | 5.20 | 5 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 83 | 84 | 49 | 48 | 15 | 24 | 76 | 6 | 1.30 | .262 | |
| Justin Masterson | CLE | 3.98 | 4 | 6 | 0 | 0 | 15 | 15 | 1 | 0 | 97.1 | 87 | 47 | 43 | 7 | 40 | 77 | 10 | 1.30 | .242 | |
| Carlos Zambrano | MIA | 4.01 | 4 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 83 | 66 | 38 | 37 | 6 | 42 | 63 | 9 | 1.30 | .224 | |
| 60 | Bronson Arroyo | CIN | 4.19 | 3 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 86 | 99 | 42 | 40 | 15 | 14 | 60 | 7 | 1.31 | .290 |
| Adam Wainwright | STL | 4.46 | 5 | 7 | 0 | 0 | 14 | 14 | 1 | 1 | 84.2 | 85 | 45 | 42 | 8 | 26 | 80 | 6 | 1.31 | .263 | |
| 62 | Paul Maholm | CHC | 4.88 | 4 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 72 | 73 | 39 | 39 | 10 | 22 | 49 | 6 | 1.32 | .267 |
| Jake Westbrook | STL | 3.83 | 6 | 6 | 0 | 0 | 14 | 14 | 1 | 0 | 87 | 92 | 42 | 37 | 7 | 23 | 59 | 9 | 1.32 | .266 | |
| 64 | Randall Delgado | ATL | 4.12 | 4 | 7 | 0 | 0 | 13 | 13 | 0 | 0 | 74.1 | 62 | 35 | 34 | 6 | 37 | 60 | 4 | 1.33 | .230 |
| 65 | Homer Bailey | CIN | 4.20 | 5 | 5 | 0 | 0 | 14 | 14 | 1 | 0 | 85.2 | 89 | 45 | 40 | 12 | 26 | 60 | 10 | 1.34 | .265 |
| Anthony Bass | SD | 4.70 | 2 | 7 | 0 | 0 | 16 | 14 | 1 | 0 | 84.1 | 80 | 51 | 44 | 8 | 33 | 72 | 4 | 1.34 | .251 | |
| Jeremy Hellickson | TB | 3.45 | 4 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 78.1 | 75 | 36 | 30 | 14 | 30 | 52 | 8 | 1.34 | .251 | |
| Phil Hughes | NYY | 4.94 | 7 | 6 | 0 | 0 | 14 | 14 | 1 | 0 | 78.1 | 85 | 47 | 43 | 19 | 20 | 77 | 6 | 1.34 | .269 | |
| Ricky Romero | TOR | 4.34 | 8 | 1 | 0 | 0 | 15 | 15 | 0 | 0 | 95.1 | 82 | 50 | 46 | 13 | 46 | 69 | 7 | 1.34 | .232 | |
| Ervin Santana | LAA | 5.16 | 4 | 7 | 0 | 0 | 14 | 14 | 1 | 1 | 89 | 83 | 52 | 51 | 18 | 36 | 61 | 6 | 1.34 | .243 | |
| 71 | Jake Arrieta | BAL | 5.83 | 3 | 9 | 0 | 0 | 15 | 15 | 0 | 0 | 88 | 94 | 60 | 57 | 12 | 25 | 79 | 5 | 1.35 | .271 |
| Felix Doubront | BOS | 4.31 | 8 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 79.1 | 79 | 42 | 38 | 11 | 28 | 85 | 8 | 1.35 | .254 | |
| Lucas Harrell | HOU | 4.77 | 6 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 88.2 | 89 | 55 | 47 | 8 | 31 | 49 | 5 | 1.35 | .261 | |
| James Shields | TB | 3.72 | 7 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 92 | 94 | 50 | 38 | 10 | 30 | 86 | 8 | 1.35 | .258 | |
| 75 | Tommy Hanson | ATL | 3.54 | 8 | 4 | 0 | 0 | 15 | 15 | 0 | 0 | 86.1 | 82 | 37 | 34 | 14 | 35 | 74 | 7 | 1.36 | .253 |
| 76 | Henderson Alvarez | TOR | 4.30 | 3 | 6 | 0 | 0 | 14 | 14 | 1 | 1 | 90 | 103 | 47 | 43 | 16 | 20 | 27 | 8 | 1.37 | .289 |
| Dan Haren | LAA | 4.24 | 5 | 7 | 0 | 0 | 15 | 15 | 1 | 1 | 93.1 | 106 | 46 | 44 | 13 | 22 | 82 | 7 | 1.37 | .289 | |
| Tommy Hunter | BAL | 5.70 | 3 | 4 | 0 | 0 | 13 | 13 | 0 | 0 | 77.1 | 91 | 53 | 49 | 18 | 15 | 41 | 5 | 1.37 | .296 | |
| Jon Lester | BOS | 4.48 | 4 | 5 | 0 | 0 | 15 | 15 | 2 | 0 | 94.1 | 102 | 52 | 47 | 8 | 27 | 75 | 9 | 1.37 | .278 | |
| Jeff Samardzija | CHC | 4.34 | 5 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 83 | 84 | 42 | 40 | 7 | 30 | 84 | 7 | 1.37 | .264 | |
| 81 | Matt Moore | TB | 4.13 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 80.2 | 71 | 44 | 37 | 11 | 40 | 85 | 6 | 1.38 | .233 |
| Ivan Nova | NYY | 4.32 | 9 | 2 | 0 | 0 | 13 | 13 | 0 | 0 | 85.1 | 95 | 41 | 41 | 14 | 23 | 73 | 7 | 1.38 | .287 | |
| Joe Saunders | ARI | 3.44 | 4 | 5 | 0 | 0 | 13 | 13 | 1 | 1 | 81 | 91 | 36 | 31 | 9 | 21 | 53 | 9 | 1.38 | .283 | |
| Jerome Williams | LAA | 4.46 | 6 | 5 | 0 | 0 | 13 | 12 | 1 | 1 | 82.2 | 88 | 44 | 41 | 7 | 26 | 56 | 8 | 1.38 | .273 | |
| 85 | Mike Leake | CIN | 4.70 | 2 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 74.2 | 83 | 44 | 39 | 9 | 21 | 53 | 6 | 1.39 | .284 |
| Kevin Millwood | SEA | 4.02 | 3 | 6 | 0 | 0 | 14 | 14 | 1 | 1 | 80.2 | 79 | 43 | 36 | 3 | 33 | 59 | 6 | 1.39 | .257 | |
| Ricky Nolasco | MIA | 5.16 | 6 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 83.2 | 92 | 49 | 48 | 10 | 24 | 50 | 7 | 1.39 | .283 | |
| 88 | Chad Billingsley | LAD | 4.15 | 4 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 86.2 | 90 | 47 | 40 | 9 | 31 | 80 | 7 | 1.40 | .268 |
| 89 | Yovani Gallardo | MIL | 4.22 | 6 | 5 | 0 | 0 | 15 | 15 | 0 | 0 | 89.2 | 88 | 44 | 42 | 12 | 38 | 90 | 12 | 1.41 | .257 |
| Mat Latos | CIN | 5.20 | 5 | 2 | 0 | 0 | 14 | 14 | 0 | 0 | 79.2 | 86 | 50 | 46 | 16 | 26 | 70 | 5 | 1.41 | .274 | |
| Mike Minor | ATL | 6.04 | 3 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 76 | 77 | 53 | 51 | 15 | 30 | 66 | 4 | 1.41 | .268 | |
| Edinson Volquez | SD | 4.11 | 3 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 87.2 | 73 | 41 | 40 | 7 | 51 | 76 | 8 | 1.41 | .229 | |
| Barry Zito | SF | 4.35 | 5 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 80.2 | 78 | 45 | 39 | 11 | 36 | 45 | 7 | 1.41 | .253 | |
| 94 | Erik Bedard | PIT | 4.13 | 4 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 72 | 70 | 34 | 33 | 5 | 32 | 69 | 5 | 1.42 | .254 |
| Bud Norris | HOU | 4.81 | 5 | 4 | 0 | 0 | 13 | 13 | 0 | 0 | 73 | 76 | 41 | 39 | 10 | 28 | 81 | 7 | 1.42 | .263 | |
| 96 | Yu Darvish | TEX | 3.45 | 9 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 88.2 | 78 | 38 | 34 | 7 | 49 | 96 | 8 | 1.43 | .234 |
| 97 | Aaron Harang | LAD | 3.76 | 5 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 81.1 | 80 | 39 | 34 | 6 | 37 | 70 | 8 | 1.44 | .256 |
| 98 | Luke Hochevar | KC | 5.65 | 4 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 78 | 87 | 50 | 49 | 6 | 27 | 60 | 6 | 1.46 | .291 |
| Josh Johnson | MIA | 4.18 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 84 | 96 | 39 | 39 | 4 | 27 | 70 | 10 | 1.46 | .296 | |
| 100 | Max Scherzer | DET | 5.17 | 6 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 78.1 | 90 | 49 | 45 | 13 | 29 | 100 | 8 | 1.52 | .288 |
| 101 | Clay Buchholz | BOS | 5.53 | 8 | 2 | 0 | 0 | 14 | 14 | 1 | 1 | 86.1 | 99 | 55 | 53 | 15 | 34 | 58 | 5 | 1.54 | .295 |
| J.A. Happ | HOU | 5.15 | 5 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 78.2 | 90 | 47 | 45 | 13 | 31 | 79 | 9 | 1.54 | .288 | |
| Tim Lincecum | SF | 6.07 | 2 | 8 | 0 | 0 | 15 | 15 | 0 | 0 | 83 | 83 | 58 | 56 | 8 | 45 | 91 | 3 | 1.54 | .256 | |
| 104 | Ubaldo Jimenez | CLE | 4.59 | 7 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 82.1 | 79 | 45 | 42 | 11 | 49 | 58 | 8 | 1.55 | .249 |
| 105 | Randy Wolf | MIL | 5.11 | 2 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 81 | 96 | 49 | 46 | 8 | 31 | 48 | 5 | 1.57 | .298 |
| 106 | Derek Lowe | CLE | 4.30 | 7 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 83.2 | 105 | 42 | 40 | 5 | 27 | 30 | 10 | 1.58 | .313 |
| Rick Porcello | DET | 4.95 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 80 | 106 | 50 | 44 | 8 | 20 | 46 | 7 | 1.58 | .319 | |
| 108 | Kyle Drabek | TOR | 4.67 | 4 | 7 | 0 | 0 | 13 | 13 | 0 | 0 | 71.1 | 67 | 41 | 37 | 10 | 47 | 47 | 6 | 1.60 | .250 |
| 109 | Brian Matusz | BAL | 5.00 | 5 | 8 | 0 | 0 | 14 | 14 | 0 | 0 | 75.2 | 87 | 49 | 42 | 10 | 35 | 59 | 6 | 1.61 | .282 |