| Career Leaders | MLB Leaders | AL Leaders | NL Leaders | Team Leaders |
| Rank | Player | Team | ERA | W | L | S | SvO | G | GS | CG | SO | IP | H | R | ER | HR | BB | K | QS | Ratio | BAVG |
| 1 | R.A. Dickey | NYM | 2.00 | 11 | 1 | 0 | 0 | 14 | 14 | 3 | 2 | 99 | 67 | 24 | 22 | 8 | 21 | 103 | 13 | 0.89 | .194 |
| 2 | Yovani Gallardo | MIL | 4.22 | 6 | 5 | 0 | 0 | 15 | 15 | 0 | 0 | 89.2 | 88 | 44 | 42 | 12 | 38 | 90 | 12 | 1.41 | .257 |
| Jake Peavy | CWS | 2.74 | 6 | 3 | 0 | 0 | 14 | 14 | 3 | 1 | 98.2 | 70 | 32 | 30 | 8 | 23 | 83 | 12 | 0.94 | .198 | |
| Justin Verlander | DET | 2.57 | 7 | 4 | 0 | 0 | 15 | 15 | 3 | 1 | 108.2 | 81 | 37 | 31 | 6 | 27 | 106 | 12 | 0.99 | .204 | |
| Ryan Vogelsong | SF | 2.41 | 6 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 89.2 | 71 | 25 | 24 | 6 | 32 | 64 | 12 | 1.15 | .219 | |
| C.J. Wilson | LAA | 2.44 | 8 | 4 | 0 | 0 | 15 | 15 | 0 | 0 | 92.1 | 67 | 31 | 25 | 4 | 39 | 79 | 12 | 1.15 | .203 | |
| Jordan Zimmermann | WAS | 2.89 | 3 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 90.1 | 84 | 32 | 29 | 11 | 17 | 64 | 12 | 1.12 | .246 | |
| 8 | Johnny Cueto | CIN | 2.38 | 8 | 3 | 0 | 0 | 14 | 14 | 2 | 0 | 94.2 | 89 | 27 | 25 | 5 | 20 | 67 | 11 | 1.15 | .251 |
| Gio Gonzalez | WAS | 2.55 | 9 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 84.2 | 55 | 24 | 24 | 1 | 34 | 101 | 11 | 1.05 | .182 | |
| Zack Greinke | MIL | 2.81 | 8 | 2 | 0 | 0 | 15 | 15 | 0 | 0 | 96 | 92 | 31 | 30 | 3 | 21 | 99 | 11 | 1.18 | .253 | |
| Stephen Strasburg | WAS | 2.46 | 9 | 1 | 0 | 0 | 14 | 14 | 0 | 0 | 84 | 65 | 26 | 23 | 6 | 22 | 110 | 11 | 1.04 | .214 | |
| 12 | Homer Bailey | CIN | 4.20 | 5 | 5 | 0 | 0 | 14 | 14 | 1 | 0 | 85.2 | 89 | 45 | 40 | 12 | 26 | 60 | 10 | 1.34 | .265 |
| Matt Cain | SF | 2.34 | 9 | 2 | 0 | 0 | 14 | 14 | 2 | 2 | 100 | 71 | 30 | 26 | 8 | 20 | 100 | 10 | 0.91 | .199 | |
| Dillon Gee | NYM | 4.27 | 5 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 90.2 | 87 | 47 | 43 | 12 | 25 | 83 | 10 | 1.24 | .250 | |
| Cole Hamels | PHI | 3.25 | 10 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 97 | 84 | 38 | 35 | 11 | 22 | 99 | 10 | 1.09 | .234 | |
| Matt Harrison | TEX | 3.41 | 9 | 3 | 0 | 0 | 14 | 14 | 1 | 1 | 92.1 | 93 | 36 | 35 | 7 | 22 | 55 | 10 | 1.25 | .261 | |
| Josh Johnson | MIA | 4.18 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 84 | 96 | 39 | 39 | 4 | 27 | 70 | 10 | 1.46 | .296 | |
| Clayton Kershaw | LAD | 2.73 | 5 | 3 | 0 | 0 | 15 | 15 | 1 | 1 | 102.1 | 78 | 34 | 31 | 10 | 25 | 95 | 10 | 1.01 | .214 | |
| Colby Lewis | TEX | 3.00 | 6 | 5 | 0 | 0 | 14 | 14 | 2 | 0 | 96 | 84 | 39 | 32 | 15 | 12 | 84 | 10 | 1.00 | .231 | |
| Kyle Lohse | STL | 2.85 | 6 | 2 | 0 | 0 | 15 | 15 | 0 | 0 | 94.2 | 90 | 33 | 30 | 8 | 15 | 54 | 10 | 1.11 | .250 | |
| Derek Lowe | CLE | 4.30 | 7 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 83.2 | 105 | 42 | 40 | 5 | 27 | 30 | 10 | 1.58 | .313 | |
| Justin Masterson | CLE | 3.98 | 4 | 6 | 0 | 0 | 15 | 15 | 1 | 0 | 97.1 | 87 | 47 | 43 | 7 | 40 | 77 | 10 | 1.30 | .242 | |
| James McDonald | PIT | 2.19 | 6 | 3 | 0 | 0 | 14 | 14 | 1 | 0 | 90.1 | 62 | 24 | 22 | 4 | 24 | 83 | 10 | 0.95 | .195 | |
| Wandy Rodriguez | HOU | 3.29 | 6 | 5 | 0 | 0 | 15 | 15 | 0 | 0 | 95.2 | 99 | 44 | 35 | 12 | 22 | 61 | 10 | 1.26 | .265 | |
| Anibal Sanchez | MIA | 3.94 | 3 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 89 | 80 | 43 | 39 | 8 | 28 | 83 | 10 | 1.21 | .242 | |
| 26 | Mark Buehrle | MIA | 3.82 | 5 | 8 | 0 | 0 | 14 | 14 | 1 | 0 | 92 | 92 | 42 | 39 | 12 | 13 | 44 | 9 | 1.14 | .263 |
| A.J. Burnett | PIT | 3.24 | 8 | 2 | 0 | 0 | 12 | 12 | 0 | 0 | 75 | 66 | 28 | 27 | 6 | 27 | 62 | 9 | 1.24 | .235 | |
| Chris Capuano | LAD | 2.71 | 8 | 2 | 0 | 0 | 14 | 14 | 0 | 0 | 86.1 | 67 | 30 | 26 | 10 | 31 | 80 | 9 | 1.14 | .217 | |
| Ryan Dempster | CHC | 2.11 | 3 | 3 | 0 | 0 | 12 | 12 | 0 | 0 | 81 | 61 | 21 | 19 | 6 | 22 | 66 | 9 | 1.02 | .204 | |
| Matt Garza | CHC | 4.07 | 3 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 77.1 | 64 | 38 | 35 | 11 | 22 | 72 | 9 | 1.11 | .223 | |
| J.A. Happ | HOU | 5.15 | 5 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 78.2 | 90 | 47 | 45 | 13 | 31 | 79 | 9 | 1.54 | .288 | |
| Edwin Jackson | WAS | 3.02 | 3 | 4 | 0 | 0 | 13 | 13 | 1 | 0 | 86.1 | 66 | 31 | 29 | 8 | 25 | 63 | 9 | 1.05 | .213 | |
| Ian Kennedy | ARI | 4.13 | 5 | 7 | 0 | 0 | 14 | 14 | 1 | 0 | 89.1 | 95 | 42 | 41 | 11 | 20 | 81 | 9 | 1.29 | .271 | |
| Jon Lester | BOS | 4.48 | 4 | 5 | 0 | 0 | 15 | 15 | 2 | 0 | 94.1 | 102 | 52 | 47 | 8 | 27 | 75 | 9 | 1.37 | .278 | |
| Lance Lynn | STL | 2.80 | 10 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 86.2 | 71 | 28 | 27 | 5 | 29 | 90 | 9 | 1.15 | .223 | |
| Shaun Marcum | MIL | 3.39 | 5 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 82.1 | 70 | 33 | 31 | 10 | 26 | 77 | 9 | 1.17 | .227 | |
| Brandon McCarthy | OAK | 2.54 | 6 | 3 | 0 | 0 | 12 | 12 | 0 | 0 | 78 | 75 | 25 | 22 | 5 | 19 | 52 | 9 | 1.21 | .252 | |
| Jonathon Niese | NYM | 3.75 | 5 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 81.2 | 75 | 37 | 34 | 13 | 29 | 79 | 9 | 1.27 | .241 | |
| David Price | TB | 3.08 | 9 | 4 | 0 | 0 | 14 | 14 | 1 | 1 | 90.2 | 84 | 33 | 31 | 7 | 31 | 82 | 9 | 1.27 | .248 | |
| Clayton Richard | SD | 3.95 | 5 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 98 | 99 | 53 | 43 | 12 | 27 | 58 | 9 | 1.29 | .259 | |
| CC Sabathia | NYY | 3.55 | 9 | 3 | 0 | 0 | 14 | 14 | 1 | 0 | 101.1 | 98 | 45 | 40 | 10 | 27 | 102 | 9 | 1.23 | .250 | |
| Chris Sale | CWS | 2.24 | 8 | 2 | 0 | 1 | 14 | 13 | 1 | 0 | 88.1 | 62 | 23 | 22 | 4 | 23 | 89 | 9 | 0.96 | .194 | |
| Joe Saunders | ARI | 3.44 | 4 | 5 | 0 | 0 | 13 | 13 | 1 | 1 | 81 | 91 | 36 | 31 | 9 | 21 | 53 | 9 | 1.38 | .283 | |
| Jered Weaver | LAA | 2.40 | 7 | 1 | 0 | 0 | 12 | 12 | 2 | 1 | 75 | 51 | 23 | 20 | 5 | 17 | 60 | 9 | 0.91 | .189 | |
| Jake Westbrook | STL | 3.83 | 6 | 6 | 0 | 0 | 14 | 14 | 1 | 0 | 87 | 92 | 42 | 37 | 7 | 23 | 59 | 9 | 1.32 | .266 | |
| Carlos Zambrano | MIA | 4.01 | 4 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 83 | 66 | 38 | 37 | 6 | 42 | 63 | 9 | 1.30 | .224 | |
| 47 | Henderson Alvarez | TOR | 4.30 | 3 | 6 | 0 | 0 | 14 | 14 | 1 | 1 | 90 | 103 | 47 | 43 | 16 | 20 | 27 | 8 | 1.37 | .289 |
| Brandon Beachy | ATL | 2.00 | 5 | 5 | 0 | 0 | 13 | 13 | 1 | 1 | 81 | 49 | 24 | 18 | 6 | 29 | 68 | 8 | 0.96 | .171 | |
| Josh Beckett | BOS | 4.14 | 4 | 7 | 0 | 0 | 12 | 12 | 0 | 0 | 78.1 | 73 | 36 | 36 | 9 | 17 | 56 | 8 | 1.15 | .247 | |
| Madison Bumgarner | SF | 2.92 | 8 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 95.2 | 83 | 36 | 31 | 8 | 19 | 78 | 8 | 1.07 | .231 | |
| Trevor Cahill | ARI | 3.47 | 6 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 90.2 | 80 | 38 | 35 | 4 | 34 | 67 | 8 | 1.26 | .245 | |
| Yu Darvish | TEX | 3.45 | 9 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 88.2 | 78 | 38 | 34 | 7 | 49 | 96 | 8 | 1.43 | .234 | |
| Felix Doubront | BOS | 4.31 | 8 | 3 | 0 | 0 | 14 | 14 | 0 | 0 | 79.1 | 79 | 42 | 38 | 11 | 28 | 85 | 8 | 1.35 | .254 | |
| Roy Halladay | PHI | 3.98 | 4 | 5 | 0 | 0 | 11 | 11 | 0 | 0 | 72.1 | 69 | 32 | 32 | 6 | 14 | 56 | 8 | 1.15 | .252 | |
| Jason Hammel | BAL | 2.61 | 8 | 2 | 0 | 0 | 14 | 14 | 1 | 1 | 89.2 | 71 | 29 | 26 | 7 | 29 | 87 | 8 | 1.12 | .215 | |
| Aaron Harang | LAD | 3.76 | 5 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 81.1 | 80 | 39 | 34 | 6 | 37 | 70 | 8 | 1.44 | .256 | |
| Jeremy Hellickson | TB | 3.45 | 4 | 3 | 0 | 0 | 13 | 13 | 0 | 0 | 78.1 | 75 | 36 | 30 | 14 | 30 | 52 | 8 | 1.34 | .251 | |
| Felix Hernandez | SEA | 3.52 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 94.2 | 92 | 39 | 37 | 9 | 30 | 91 | 8 | 1.29 | .256 | |
| Ubaldo Jimenez | CLE | 4.59 | 7 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 82.1 | 79 | 45 | 42 | 11 | 49 | 58 | 8 | 1.55 | .249 | |
| Hiroki Kuroda | NYY | 3.57 | 6 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 88.1 | 86 | 38 | 35 | 12 | 28 | 62 | 8 | 1.29 | .257 | |
| Wade Miley | ARI | 2.30 | 8 | 3 | 0 | 0 | 14 | 11 | 0 | 0 | 82.1 | 70 | 24 | 21 | 3 | 17 | 57 | 8 | 1.06 | .225 | |
| Brandon Morrow | TOR | 3.01 | 7 | 4 | 0 | 0 | 13 | 13 | 3 | 3 | 77.2 | 54 | 28 | 26 | 7 | 24 | 67 | 8 | 1.00 | .194 | |
| Jarrod Parker | OAK | 2.70 | 3 | 3 | 0 | 0 | 11 | 11 | 0 | 0 | 66.2 | 50 | 20 | 20 | 2 | 32 | 49 | 8 | 1.23 | .214 | |
| Johan Santana | NYM | 3.00 | 5 | 3 | 0 | 0 | 14 | 14 | 2 | 2 | 84 | 66 | 30 | 28 | 8 | 28 | 84 | 8 | 1.12 | .214 | |
| Max Scherzer | DET | 5.17 | 6 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 78.1 | 90 | 49 | 45 | 13 | 29 | 100 | 8 | 1.52 | .288 | |
| James Shields | TB | 3.72 | 7 | 4 | 0 | 0 | 14 | 14 | 0 | 0 | 92 | 94 | 50 | 38 | 10 | 30 | 86 | 8 | 1.35 | .258 | |
| Jason Vargas | SEA | 4.66 | 7 | 7 | 0 | 0 | 16 | 16 | 0 | 0 | 102.1 | 98 | 53 | 53 | 20 | 27 | 64 | 8 | 1.22 | .254 | |
| Edinson Volquez | SD | 4.11 | 3 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 87.2 | 73 | 41 | 40 | 7 | 51 | 76 | 8 | 1.41 | .229 | |
| Jerome Williams | LAA | 4.46 | 6 | 5 | 0 | 0 | 13 | 12 | 1 | 1 | 82.2 | 88 | 44 | 41 | 7 | 26 | 56 | 8 | 1.38 | .273 | |
| Vance Worley | PHI | 2.78 | 3 | 4 | 0 | 0 | 11 | 11 | 0 | 0 | 68 | 62 | 26 | 21 | 8 | 23 | 61 | 8 | 1.25 | .245 | |
| 71 | Bronson Arroyo | CIN | 4.19 | 3 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 86 | 99 | 42 | 40 | 15 | 14 | 60 | 7 | 1.31 | .290 |
| Chad Billingsley | LAD | 4.15 | 4 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 86.2 | 90 | 47 | 40 | 9 | 31 | 80 | 7 | 1.40 | .268 | |
| Bruce Chen | KC | 4.81 | 6 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 82.1 | 88 | 45 | 44 | 9 | 18 | 59 | 7 | 1.29 | .272 | |
| Wei-Yin Chen | BAL | 3.36 | 7 | 2 | 0 | 0 | 13 | 13 | 0 | 0 | 80.1 | 79 | 34 | 30 | 8 | 25 | 57 | 7 | 1.29 | .256 | |
| Bartolo Colon | OAK | 4.22 | 6 | 7 | 0 | 0 | 15 | 15 | 0 | 0 | 89.2 | 101 | 43 | 42 | 12 | 16 | 55 | 7 | 1.30 | .283 | |
| Tommy Hanson | ATL | 3.54 | 8 | 4 | 0 | 0 | 15 | 15 | 0 | 0 | 86.1 | 82 | 37 | 34 | 14 | 35 | 74 | 7 | 1.36 | .253 | |
| Dan Haren | LAA | 4.24 | 5 | 7 | 0 | 0 | 15 | 15 | 1 | 1 | 93.1 | 106 | 46 | 44 | 13 | 22 | 82 | 7 | 1.37 | .289 | |
| Cliff Lee | PHI | 3.48 | 0 | 3 | 0 | 0 | 11 | 11 | 0 | 0 | 77.2 | 73 | 30 | 30 | 9 | 14 | 77 | 7 | 1.12 | .253 | |
| Tommy Milone | OAK | 4.13 | 7 | 5 | 0 | 0 | 14 | 14 | 1 | 0 | 89.1 | 84 | 43 | 41 | 13 | 24 | 52 | 7 | 1.21 | .247 | |
| Ricky Nolasco | MIA | 5.16 | 6 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 83.2 | 92 | 49 | 48 | 10 | 24 | 50 | 7 | 1.39 | .283 | |
| Bud Norris | HOU | 4.81 | 5 | 4 | 0 | 0 | 13 | 13 | 0 | 0 | 73 | 76 | 41 | 39 | 10 | 28 | 81 | 7 | 1.42 | .263 | |
| Ivan Nova | NYY | 4.32 | 9 | 2 | 0 | 0 | 13 | 13 | 0 | 0 | 85.1 | 95 | 41 | 41 | 14 | 23 | 73 | 7 | 1.38 | .287 | |
| Rick Porcello | DET | 4.95 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 80 | 106 | 50 | 44 | 8 | 20 | 46 | 7 | 1.58 | .319 | |
| Ricky Romero | TOR | 4.34 | 8 | 1 | 0 | 0 | 15 | 15 | 0 | 0 | 95.1 | 82 | 50 | 46 | 13 | 46 | 69 | 7 | 1.34 | .232 | |
| Jeff Samardzija | CHC | 4.34 | 5 | 6 | 0 | 0 | 14 | 14 | 0 | 0 | 83 | 84 | 42 | 40 | 7 | 30 | 84 | 7 | 1.37 | .264 | |
| Barry Zito | SF | 4.35 | 5 | 5 | 0 | 0 | 14 | 14 | 1 | 1 | 80.2 | 78 | 45 | 39 | 11 | 36 | 45 | 7 | 1.41 | .253 | |
| 87 | Joe Blanton | PHI | 5.04 | 6 | 6 | 0 | 0 | 15 | 14 | 2 | 1 | 91 | 102 | 55 | 51 | 17 | 12 | 74 | 6 | 1.25 | .277 |
| Kevin Correia | PIT | 4.12 | 3 | 6 | 0 | 0 | 13 | 13 | 0 | 0 | 74.1 | 74 | 36 | 34 | 12 | 22 | 27 | 6 | 1.29 | .261 | |
| Scott Diamond | MIN | 2.57 | 5 | 3 | 0 | 0 | 9 | 9 | 0 | 0 | 56 | 62 | 22 | 16 | 7 | 8 | 30 | 6 | 1.25 | .279 | |
| Kyle Drabek | TOR | 4.67 | 4 | 7 | 0 | 0 | 13 | 13 | 0 | 0 | 71.1 | 67 | 41 | 37 | 10 | 47 | 47 | 6 | 1.60 | .250 | |
| Doug Fister | DET | 2.72 | 1 | 4 | 0 | 0 | 8 | 8 | 0 | 0 | 46.1 | 48 | 17 | 14 | 4 | 10 | 37 | 6 | 1.25 | .264 | |
| Gavin Floyd | CWS | 5.20 | 5 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 83 | 84 | 49 | 48 | 15 | 24 | 76 | 6 | 1.30 | .262 | |
| Jaime Garcia | STL | 4.48 | 3 | 4 | 0 | 0 | 11 | 11 | 0 | 0 | 66.1 | 78 | 34 | 33 | 2 | 19 | 51 | 6 | 1.46 | .304 | |
| Luke Hochevar | KC | 5.65 | 4 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 78 | 87 | 50 | 49 | 6 | 27 | 60 | 6 | 1.46 | .291 | |
| Derek Holland | TEX | 5.10 | 5 | 4 | 0 | 0 | 12 | 11 | 0 | 0 | 67 | 65 | 42 | 38 | 11 | 24 | 59 | 6 | 1.33 | .251 | |
| Phil Hughes | NYY | 4.94 | 7 | 6 | 0 | 0 | 14 | 14 | 1 | 0 | 78.1 | 85 | 47 | 43 | 19 | 20 | 77 | 6 | 1.34 | .269 | |
| Mike Leake | CIN | 4.70 | 2 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 74.2 | 83 | 44 | 39 | 9 | 21 | 53 | 6 | 1.39 | .284 | |
| Ted Lilly | LAD | 3.14 | 5 | 1 | 0 | 0 | 8 | 8 | 0 | 0 | 48.2 | 36 | 23 | 17 | 3 | 19 | 31 | 6 | 1.13 | .203 | |
| Paul Maholm | CHC | 4.88 | 4 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 72 | 73 | 39 | 39 | 10 | 22 | 49 | 6 | 1.32 | .267 | |
| Brian Matusz | BAL | 5.00 | 5 | 8 | 0 | 0 | 14 | 14 | 0 | 0 | 75.2 | 87 | 49 | 42 | 10 | 35 | 59 | 6 | 1.61 | .282 | |
| Kevin Millwood | SEA | 4.02 | 3 | 6 | 0 | 0 | 14 | 14 | 1 | 1 | 80.2 | 79 | 43 | 36 | 3 | 33 | 59 | 6 | 1.39 | .257 | |
| Matt Moore | TB | 4.13 | 4 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 80.2 | 71 | 44 | 37 | 11 | 40 | 85 | 6 | 1.38 | .233 | |
| Hector Noesi | SEA | 5.69 | 2 | 8 | 0 | 0 | 14 | 14 | 0 | 0 | 80.2 | 73 | 52 | 51 | 15 | 30 | 50 | 6 | 1.28 | .246 | |
| Ervin Santana | LAA | 5.16 | 4 | 7 | 0 | 0 | 14 | 14 | 1 | 1 | 89 | 83 | 52 | 51 | 18 | 36 | 61 | 6 | 1.34 | .243 | |
| Adam Wainwright | STL | 4.46 | 5 | 7 | 0 | 0 | 14 | 14 | 1 | 1 | 84.2 | 85 | 45 | 42 | 8 | 26 | 80 | 6 | 1.31 | .263 | |
| 106 | Jake Arrieta | BAL | 5.83 | 3 | 9 | 0 | 0 | 15 | 15 | 0 | 0 | 88 | 94 | 60 | 57 | 12 | 25 | 79 | 5 | 1.35 | .271 |
| Erik Bedard | PIT | 4.13 | 4 | 7 | 0 | 0 | 14 | 14 | 0 | 0 | 72 | 70 | 34 | 33 | 5 | 32 | 69 | 5 | 1.42 | .254 | |
| Clay Buchholz | BOS | 5.53 | 8 | 2 | 0 | 0 | 14 | 14 | 1 | 1 | 86.1 | 99 | 55 | 53 | 15 | 34 | 58 | 5 | 1.54 | .295 | |
| Lucas Harrell | HOU | 4.77 | 6 | 6 | 0 | 0 | 15 | 15 | 0 | 0 | 88.2 | 89 | 55 | 47 | 8 | 31 | 49 | 5 | 1.35 | .261 | |
| Tim Hudson | ATL | 3.88 | 5 | 3 | 0 | 0 | 10 | 10 | 1 | 1 | 65 | 59 | 30 | 28 | 2 | 20 | 44 | 5 | 1.22 | .242 | |
| Philip Humber | CWS | 6.01 | 3 | 4 | 0 | 0 | 12 | 12 | 1 | 1 | 67.1 | 69 | 46 | 45 | 12 | 31 | 63 | 5 | 1.49 | .261 | |
| Tommy Hunter | BAL | 5.70 | 3 | 4 | 0 | 0 | 13 | 13 | 0 | 0 | 77.1 | 91 | 53 | 49 | 18 | 15 | 41 | 5 | 1.37 | .296 | |
| Mat Latos | CIN | 5.20 | 5 | 2 | 0 | 0 | 14 | 14 | 0 | 0 | 79.2 | 86 | 50 | 46 | 16 | 26 | 70 | 5 | 1.41 | .274 | |
| Jason Marquis | SD | 6.08 | 3 | 6 | 0 | 0 | 10 | 10 | 0 | 0 | 53.1 | 72 | 39 | 36 | 10 | 22 | 32 | 5 | 1.76 | .333 | |
| Andy Pettitte | NYY | 3.29 | 3 | 3 | 0 | 0 | 8 | 8 | 0 | 0 | 54.2 | 46 | 21 | 20 | 7 | 14 | 52 | 5 | 1.10 | .228 | |
| Tyson Ross | OAK | 6.11 | 2 | 6 | 0 | 0 | 10 | 10 | 0 | 0 | 53 | 67 | 36 | 36 | 7 | 25 | 29 | 5 | 1.74 | .318 | |
| Drew Smyly | DET | 3.96 | 2 | 2 | 0 | 0 | 12 | 12 | 0 | 0 | 63.2 | 63 | 30 | 28 | 10 | 18 | 58 | 5 | 1.27 | .259 | |
| Josh Tomlin | CLE | 5.12 | 3 | 4 | 0 | 0 | 11 | 10 | 0 | 0 | 63.1 | 74 | 37 | 36 | 8 | 15 | 38 | 5 | 1.41 | .291 | |
| Randy Wolf | MIL | 5.11 | 2 | 5 | 0 | 0 | 14 | 14 | 0 | 0 | 81 | 96 | 49 | 46 | 8 | 31 | 48 | 5 | 1.57 | .298 | |
| 120 | Anthony Bass | SD | 4.70 | 2 | 7 | 0 | 0 | 16 | 14 | 1 | 0 | 84.1 | 80 | 51 | 44 | 8 | 33 | 72 | 4 | 1.34 | .251 |
| Blake Beavan | SEA | 5.92 | 3 | 6 | 0 | 0 | 12 | 12 | 0 | 0 | 62.1 | 77 | 41 | 41 | 12 | 11 | 30 | 4 | 1.41 | .297 | |
| John Danks | CWS | 5.70 | 3 | 4 | 0 | 0 | 9 | 9 | 0 | 0 | 53.2 | 57 | 35 | 34 | 7 | 23 | 30 | 4 | 1.49 | .273 | |
| Randall Delgado | ATL | 4.12 | 4 | 7 | 0 | 0 | 13 | 13 | 0 | 0 | 74.1 | 62 | 35 | 34 | 6 | 37 | 60 | 4 | 1.33 | .230 | |
| Ross Detwiler | WAS | 3.34 | 4 | 3 | 0 | 0 | 15 | 9 | 0 | 0 | 62 | 54 | 28 | 23 | 6 | 21 | 46 | 4 | 1.21 | .236 | |
| Nathan Eovaldi | LAD | 2.35 | 0 | 3 | 0 | 0 | 5 | 5 | 0 | 0 | 30.2 | 28 | 9 | 8 | 2 | 12 | 20 | 4 | 1.30 | .243 | |
| Neftali Feliz | TEX | 3.16 | 3 | 1 | 0 | 0 | 8 | 7 | 1 | 0 | 42.2 | 28 | 15 | 15 | 5 | 23 | 37 | 4 | 1.20 | .187 | |
| Jeanmar Gomez | CLE | 4.95 | 4 | 6 | 0 | 0 | 13 | 12 | 0 | 0 | 67.1 | 69 | 43 | 37 | 8 | 25 | 32 | 4 | 1.40 | .264 | |
| Drew Hutchison | TOR | 4.60 | 5 | 3 | 0 | 0 | 11 | 11 | 0 | 0 | 58.2 | 59 | 31 | 30 | 8 | 20 | 49 | 4 | 1.35 | .257 | |
| Kyle Kendrick | PHI | 5.29 | 2 | 7 | 0 | 1 | 15 | 10 | 1 | 1 | 63 | 74 | 41 | 37 | 8 | 23 | 40 | 4 | 1.54 | .301 | |
| Francisco Liriano | MIN | 5.74 | 1 | 7 | 0 | 0 | 16 | 11 | 0 | 0 | 64.1 | 60 | 43 | 41 | 7 | 38 | 65 | 4 | 1.52 | .252 | |
| Jordan Lyles | HOU | 5.04 | 1 | 4 | 0 | 0 | 8 | 8 | 0 | 0 | 44.2 | 48 | 32 | 25 | 6 | 16 | 26 | 4 | 1.43 | .271 | |
| Mike Minor | ATL | 6.04 | 3 | 5 | 0 | 0 | 13 | 13 | 0 | 0 | 76 | 77 | 53 | 51 | 15 | 30 | 66 | 4 | 1.41 | .268 | |
| Juan Nicasio | COL | 5.28 | 2 | 3 | 0 | 0 | 11 | 11 | 0 | 0 | 58 | 72 | 37 | 34 | 7 | 22 | 54 | 4 | 1.62 | .313 | |
| Felipe Paulino | KC | 1.67 | 3 | 1 | 0 | 0 | 7 | 7 | 0 | 0 | 37.2 | 31 | 8 | 7 | 3 | 15 | 39 | 4 | 1.22 | .223 | |
| Carl Pavano | MIN | 6.00 | 2 | 5 | 0 | 0 | 11 | 11 | 0 | 0 | 63 | 80 | 46 | 42 | 9 | 8 | 33 | 4 | 1.40 | .313 | |
| P.J. Walters | MIN | 5.40 | 2 | 2 | 0 | 0 | 7 | 7 | 1 | 0 | 36.2 | 42 | 22 | 22 | 7 | 14 | 23 | 4 | 1.53 | .300 | |
| Travis Wood | CHC | 4.14 | 1 | 3 | 0 | 0 | 7 | 7 | 0 | 0 | 41.1 | 33 | 19 | 19 | 7 | 19 | 29 | 4 | 1.26 | .224 | |
| 138 | Daniel Bard | BOS | 5.24 | 5 | 6 | 0 | 0 | 11 | 10 | 0 | 0 | 55 | 52 | 33 | 32 | 6 | 37 | 34 | 3 | 1.62 | .259 |
| Christian Friedrich | COL | 5.65 | 4 | 4 | 0 | 0 | 9 | 9 | 0 | 0 | 51 | 63 | 35 | 32 | 8 | 19 | 49 | 3 | 1.61 | .306 | |
| Daniel Hudson | ARI | 6.60 | 3 | 1 | 0 | 0 | 8 | 8 | 0 | 0 | 43.2 | 55 | 32 | 32 | 8 | 12 | 34 | 3 | 1.53 | .313 | |
| Tim Lincecum | SF | 6.07 | 2 | 8 | 0 | 0 | 15 | 15 | 0 | 0 | 83 | 83 | 58 | 56 | 8 | 45 | 91 | 3 | 1.54 | .256 | |
| Cory Luebke | SD | 2.61 | 3 | 1 | 0 | 0 | 5 | 5 | 0 | 0 | 31 | 28 | 10 | 9 | 1 | 8 | 23 | 3 | 1.16 | .233 | |
| Charlie Morton | PIT | 4.65 | 2 | 6 | 0 | 0 | 9 | 9 | 0 | 0 | 50.1 | 62 | 30 | 26 | 5 | 11 | 25 | 3 | 1.45 | .305 | |
| Jamie Moyer | COL | 5.70 | 2 | 5 | 0 | 0 | 10 | 10 | 0 | 0 | 53.2 | 75 | 40 | 34 | 11 | 18 | 36 | 3 | 1.73 | .328 | |
| Jose Quintana | CWS | 1.53 | 2 | 1 | 0 | 0 | 7 | 5 | 0 | 0 | 35.1 | 30 | 6 | 6 | 2 | 6 | 20 | 3 | 1.02 | .238 | |
| Eric Stults | SD | 3.19 | 1 | 2 | 0 | 0 | 6 | 5 | 0 | 0 | 31 | 28 | 15 | 11 | 4 | 11 | 13 | 3 | 1.26 | .250 | |
| Alex White | COL | 6.06 | 2 | 5 | 0 | 0 | 9 | 9 | 0 | 0 | 49 | 58 | 36 | 33 | 8 | 18 | 31 | 3 | 1.55 | .293 | |
| 148 | Travis Blackley | OAK | 3.89 | 1 | 2 | 0 | 0 | 12 | 5 | 0 | 0 | 39.1 | 35 | 20 | 17 | 1 | 10 | 25 | 2 | 1.14 | .236 |
| Alex Cobb | TB | 3.82 | 3 | 3 | 0 | 0 | 6 | 6 | 0 | 0 | 37.2 | 32 | 18 | 16 | 2 | 12 | 32 | 2 | 1.17 | .227 | |
| Danny Duffy | KC | 3.90 | 2 | 2 | 0 | 0 | 6 | 6 | 0 | 0 | 27.2 | 26 | 13 | 12 | 2 | 18 | 28 | 2 | 1.59 | .252 | |
| Michael Fiers | MIL | 3.46 | 2 | 2 | 0 | 0 | 5 | 4 | 0 | 0 | 26 | 27 | 10 | 10 | 2 | 4 | 24 | 2 | 1.19 | .265 | |
| Jeremy Guthrie | COL | 6.68 | 3 | 6 | 0 | 0 | 12 | 11 | 0 | 0 | 62 | 85 | 52 | 46 | 15 | 23 | 32 | 2 | 1.74 | .326 | |
| Jeremy Hefner | NYM | 5.84 | 1 | 3 | 0 | 0 | 6 | 3 | 0 | 0 | 24.2 | 32 | 17 | 16 | 2 | 2 | 15 | 2 | 1.38 | .302 | |
| Vin Mazzaro | KC | 5.24 | 3 | 2 | 0 | 0 | 6 | 5 | 0 | 0 | 22.1 | 25 | 14 | 13 | 0 | 11 | 15 | 2 | 1.61 | .294 | |
| Zach McAllister | CLE | 3.96 | 1 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 25 | 25 | 14 | 11 | 1 | 6 | 22 | 2 | 1.24 | .255 | |
| Luis Mendoza | KC | 4.69 | 2 | 3 | 0 | 0 | 12 | 7 | 0 | 0 | 55.2 | 61 | 33 | 29 | 4 | 28 | 28 | 2 | 1.60 | .284 | |
| Mike Pelfrey | NYM | 2.29 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 19.2 | 24 | 5 | 5 | 0 | 4 | 13 | 2 | 1.42 | .300 | |
| Garrett Richards | LAA | 0.86 | 2 | 0 | 0 | 0 | 4 | 3 | 0 | 0 | 21 | 13 | 3 | 2 | 1 | 11 | 17 | 2 | 1.14 | .183 | |
| Joe Wieland | SD | 4.55 | 0 | 4 | 0 | 0 | 5 | 5 | 0 | 0 | 27.2 | 26 | 16 | 14 | 5 | 9 | 24 | 2 | 1.27 | .245 | |
| 160 | Chris Archer | TB | 1.50 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6 | 3 | 3 | 1 | 0 | 1 | 7 | 1 | 0.67 | .143 |
| Miguel Batista | NYM | 4.08 | 1 | 1 | 0 | 0 | 21 | 4 | 0 | 0 | 35.1 | 35 | 18 | 16 | 4 | 22 | 25 | 1 | 1.61 | .267 | |
| Nick Blackburn | MIN | 7.45 | 4 | 4 | 0 | 0 | 11 | 11 | 0 | 0 | 54.1 | 73 | 45 | 45 | 11 | 21 | 26 | 1 | 1.73 | .323 | |
| Jhoulys Chacin | COL | 7.30 | 0 | 3 | 0 | 0 | 5 | 5 | 0 | 0 | 24.2 | 31 | 20 | 20 | 7 | 15 | 22 | 1 | 1.86 | .304 | |
| Patrick Corbin | ARI | 5.27 | 2 | 3 | 0 | 0 | 5 | 5 | 0 | 0 | 27.1 | 32 | 16 | 16 | 3 | 9 | 18 | 1 | 1.50 | .288 | |
| Marco Estrada | MIL | 4.50 | 0 | 3 | 0 | 0 | 11 | 6 | 0 | 0 | 36 | 33 | 19 | 18 | 9 | 7 | 34 | 1 | 1.11 | .241 | |
| Dana Eveland | BAL | 3.24 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 0 | 25 | 22 | 10 | 9 | 1 | 11 | 13 | 1 | 1.32 | .239 | |
| Scott Feldman | TEX | 6.00 | 1 | 6 | 0 | 0 | 13 | 8 | 0 | 0 | 42 | 48 | 35 | 28 | 5 | 14 | 32 | 1 | 1.48 | .276 | |
| Graham Godfrey | OAK | 6.43 | 0 | 4 | 0 | 0 | 5 | 4 | 0 | 0 | 21 | 26 | 18 | 15 | 4 | 10 | 10 | 1 | 1.71 | .317 | |
| Justin Grimm | TEX | 4.50 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6 | 6 | 3 | 3 | 1 | 0 | 7 | 1 | 1.00 | .261 | |
| Eric Hacker | SF | 4.50 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6 | 8 | 3 | 3 | 0 | 2 | 7 | 1 | 1.67 | .320 | |
| Liam Hendriks | MIN | 7.39 | 0 | 4 | 0 | 0 | 6 | 6 | 0 | 0 | 28 | 46 | 29 | 23 | 9 | 5 | 17 | 1 | 1.82 | .371 | |
| Jair Jurrjens | ATL | 6.75 | 1 | 2 | 0 | 0 | 5 | 5 | 0 | 0 | 24 | 33 | 18 | 18 | 5 | 11 | 12 | 1 | 1.83 | .333 | |
| Jeff Karstens | PIT | 4.50 | 0 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 12 | 15 | 6 | 6 | 0 | 2 | 5 | 1 | 1.42 | .313 | |
| Joe Kelly | STL | 3.52 | 1 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 15.1 | 23 | 7 | 6 | 2 | 2 | 8 | 1 | 1.63 | .343 | |
| Brad Lincoln | PIT | 3.82 | 3 | 2 | 0 | 0 | 17 | 4 | 0 | 0 | 37.2 | 39 | 17 | 16 | 6 | 12 | 36 | 1 | 1.35 | .264 | |
| Daisuke Matsuzaka | BOS | 6.06 | 0 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 16.1 | 13 | 11 | 11 | 2 | 5 | 15 | 1 | 1.10 | .213 | |
| Jeff Niemann | TB | 3.38 | 2 | 3 | 0 | 0 | 7 | 7 | 0 | 0 | 34.2 | 29 | 17 | 13 | 2 | 12 | 30 | 1 | 1.18 | .221 | |
| Roy Oswalt | TEX | 1.35 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6.2 | 9 | 1 | 1 | 0 | 1 | 6 | 1 | 1.50 | .321 | |
| Drew Pomeranz | COL | 4.70 | 0 | 2 | 0 | 0 | 5 | 5 | 0 | 0 | 23 | 25 | 13 | 12 | 2 | 15 | 20 | 1 | 1.74 | .281 | |
| Aneury Rodriguez | HOU | 3.00 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6 | 2 | 2 | 2 | 2 | 2 | 6 | 1 | 0.67 | .105 | |
| Jonathan Sanchez | KC | 5.70 | 1 | 3 | 0 | 0 | 8 | 8 | 0 | 0 | 36.1 | 38 | 24 | 23 | 3 | 28 | 25 | 1 | 1.82 | .273 | |
| Will Smith | KC | 9.00 | 1 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 14 | 18 | 14 | 14 | 6 | 5 | 9 | 1 | 1.64 | .300 | |
| Jeff Suppan | SD | 5.28 | 2 | 3 | 0 | 0 | 6 | 6 | 0 | 0 | 30.2 | 34 | 19 | 18 | 4 | 13 | 7 | 1 | 1.53 | .281 | |
| Chris Volstad | CHC | 7.46 | 0 | 6 | 0 | 0 | 8 | 8 | 0 | 0 | 41 | 51 | 36 | 34 | 3 | 15 | 24 | 1 | 1.61 | .302 | |
| Kyle Weiland | HOU | 6.62 | 0 | 3 | 0 | 0 | 3 | 3 | 0 | 0 | 17.2 | 24 | 13 | 13 | 5 | 7 | 13 | 1 | 1.75 | .333 | |
| Chris Young | NYM | 3.06 | 1 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 17.2 | 24 | 8 | 6 | 0 | 5 | 8 | 1 | 1.64 | .320 |